Quality and Regulatory Solutions

Senior regulatory and quality leadership for medical device teams.

Guardian QRS helps medtech companies build compliant quality systems, clear regulatory submissions, and reach the market faster, without losing sight of what matters most: getting safe devices to patients.

FDA QMSRISO 13485EU MDR / PRRCMDSAP510(k) & CE Mark

What we do

Solutions That Move You Forward

From first quality system to global market access, Guardian QRS delivers the regulatory and quality work early-stage medtech teams need, with the judgment of an in-house director.

QMS

ISO 13485 Quality Systems

Build, remediate, and maintain a quality management system that is audit-ready and right-sized for your stage.

FDA

QMSR / 21 CFR Part 820

Readiness assessments and transition support for the FDA Quality Management System Regulation, effective February 2026.

Europe

EU MDR & PRRC

Technical documentation, conformity strategy, and named Article 15 Person Responsible for Regulatory Compliance accountability.

Global

MDSAP

Single-audit readiness across the United States, Canada, Australia, Brazil, and Japan, mapped to one program.

Risk

Risk Management (ISO 14971)

Risk management files and processes that connect to design, production, and post-market, and hold up under scrutiny.

Submissions

510(k) & CE Mark

Submission strategy, gap analysis, and authoring, from planning through clearance or certification.

Safety

IEC 60601

Navigate electrical medical device safety and essential performance testing with your test lab and design team.

Emerging

Quality & Regulatory AI

Governance for AI-enabled devices and internal AI tools, aligned to ISO/IEC 42001 and evolving FDA expectations.

QMSR Readiness Assessment

A fixed-scope engagement that benchmarks your quality system against the new FDA QMSR and ISO 13485:2016, with a prioritized, practical remediation roadmap you can act on immediately.

Start an assessment

Fractional Regulatory Officer

Embedded, part-time regulatory and quality leadership with a real title and real authority. Senior direction for teams that are not ready to hire a full-time VP or Director.

Discuss a fractional role

Your QRS Solutions Architect

Practical SolutionsReal Results

Guardian QRS is the regulatory and quality partner for medical device companies that need senior expertise without a senior-level headcount. Founded by Christopher A. Henderson, the practice brings deep, hands-on experience across FDA QMSR, ISO 13485, EU MDR and PRRC accountability, and MDSAP to teams building real products under real deadlines. The work is practical and outcomes-first: quality systems that fit how you actually operate, submissions built to clear, and defensible records that stand up to auditors and notified bodies. Whether you are standing up a QMS for the first time, preparing for a submission, or need a named regulatory leader to carry accountability, Guardian QRS helps you move to market with confidence and keep patients safe.

Christopher A. Henderson Senior Solutions Architect, Guardian QRS

Built for early-stage medtech

  • Senior regulatory judgment, sized to a startup budget
  • Named accountability, including EU MDR Article 15 PRRC
  • Systems designed to scale into an eQMS, not to be rebuilt
  • Clear next steps, not compliance theater
  • Based in Denver, Colorado, serving clients anywhere

Get in touch

Let us map your path to market.

Tell us where you are and where you need to be. We will follow up to schedule a short, no-pressure consultation.